Bosses in Salt and Sanctuary are powerful enemies that are difficult to defeat. They have unique drops and can be found all through out the game.
The bosses marked with an asterisk (*) are optional. I tried rearranging the order to make it more accurate but the site wouldn't carry over images or formatting. The bosses with asterisks are OPTIONAL but routing around them may be hard to do on your first run.
The False Jester and Kraekan Cyclops are marked with two asterisks (**), because they are the only bosses that become optional once the other is defeated.
Defeating the False Jester requires beating the Mad Alchemist and routing towards him.
The Kraekan Cyclops can be reached by going on the lowest level of the Watching Woods and jumping across the falling platforms. You will reach a house in the background, walk forward and you will see a small jump then a bigger jump. You should be able to survive the large jump. After this you will skip the Mad Alchemist and go directly into the Kraekan Cyclops boss fight.
Can only be fought once per save file as NG+ will start you directly on the beach